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Uncharacterized protein KIAA0930 (KIAA0930)
- Target
- KIAA0930
- Molecular classification
- Other
01
Overview
Uncharacterized protein KIAA0930 is a cytosolic protein encoded by the KIAA0930 gene on chromosome 22 (22q13.31), without any established domains or signaling motifs[1][3][4]. It contains a domain of unknown function (DUF2045). Disease associations include Acheiropody and Cranioectodermal dysplasia 1, and it has been implicated in some cancer-associated gene fusions (e.g., KIAA0930-SMC1B), but its biological function remains unclear, and it is not currently recognized as a therapeutic target or a receptor, enzyme, transporter, or transcription factor[1][3][4][5]. KIAA0930 is localized in the cytosol and is not a secreted protein[4]. Protein interaction data suggest weak or indirect association with various cell signaling adapter proteins, but a specific role has not been verified[2].
- Other names
- C22orf9LSC3bK268H5.C22.1KIAA0930-SMC1B
02
Biological functions
Unknownpossible involvement in cytosolic processesmay regulate secretion (not confirmed)
03
Disease associations
Cancer (through gene fusions)AcheiropodyCranioectodermal dysplasia 1
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