Uncharacterized transcript antisense to MTHFD1L (ENSG00000223598)

LOC102723831 (ENSG00000223598) is an uncharacterized antisense long non-coding RNA (lncRNA) transcript located antisense to the MTHFD1L gene. As a transcript of unknown coding potential, and as no protein product or biological function has been described, its role in physiology or disease is currently unclear. There is no evidence that the transcript itself acts as a therapeutic target, nor have drugs, disease roles, or biomarkers been associated with it. The related sense gene, MTHFD1L, encodes a mitochondrial enzyme involved in one-carbon metabolism and folate cycling, essential for nucleotide biosynthesis and cellular methylation processes[5][7][4][1]. Some disease relevance for the *sense* gene (MTHFD1L), such as association with neural tube defects, exists, but this does not apply to the antisense transcript, which is currently annotated as "uncharacterized" in gene databases and appears to be only a predicted or poorly studied RNA without known function or clinical significance[5].

Other names

LOC102723831novel transcript antisense to MTHFD1L