Undesirable gut bacteria

"Undesirable gut bacteria" refers collectively to bacterial species in the intestinal microbiome that, when overgrown or unbalanced, are associated with disease states, including inflammation, metabolic disease, neurodegenerative disorders, and infections. This is not a specific molecular target but a descriptive state of microbiome imbalance (dysbiosis), in which pathogenic or pro-inflammatory bacteria predominate over beneficial commensals, disrupting normal gut and systemic functions. Therapeutic approaches are focused on modulating the overall microbiota composition rather than targeting a discrete protein or receptor.

Other names

Harmful gut bacteriaPathogenic gut bacteria“Bad” gut bacteria

Suppression or elimination of undesirable species through antibiotics; Restoration of microbiome balance (e.g., by FMT or probiotics); Modulation of bacterial metabolites (e.g., inhibition of TMA production to reduce TMAO-linked atherogenesis)