Target intelligence / Profile preview

Undisclosed dual renal cell carcinoma tumor-associated antigens

Overview

Other names: Undisclosed dual RCC antigensDual renal cell carcinoma tumor-associated antigensUndisclosed dual-targeting RCC antigens

T-cell engagement and redirection of cytotoxic activity toward tumor cells expressing the dual antigens

Cell proliferationCell signalingImmune responseOther

Cancer

Cytokine release syndrome (CRS)On-target off-tumor toxicityNeurotoxicityAntigen escape

HPN-212

Antigen expression on tumor tissueSoluble antigen levelsT-cell activation markers

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