Target intelligence / Profile preview

Undisclosed hematological tumor antigen (HC111)

Molecular classification
Receptor, Cell surface protein
01

Overview

Other names
Undisclosed cancer cell surface antigen recognized by the HC111 CARHC111 target antigenProprietary hematological tumor antigen
02

Biological functions

Cell-cell signalingTumor cell survivalOther
03

Disease associations

CancerHematological NeoplasmsLeukemiaLymphoma
04

Safety considerations

On-target off-tumor toxicityCytokine release syndrome (low risk)Immune effector cell-associated neurotoxicity syndrome (low risk)
05

Interacting drugs

HC111 (iPSC-CAR-NK)
06

Biomarkers

Target antigen expression on tumor cells

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