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Target intelligence / Profile preview
Upstream-binding factor 1-like protein 1 (UBTFL1)
- Target
- UBTFL1
- Molecular classification
- Transcription factor
01
Overview
Upstream-binding factor 1-like protein 1 (UBTFL1) is a transcription factor predicted to enable specific DNA binding and general transcription initiation activity with RNA polymerase I[1][3]. It is essential for the proliferation of the inner cell mass and trophectodermal cells during peri-implantation development[2][6][7]. UBTFL1 is primarily active in the nucleus and is involved in the regulation of gene expression, blastocyst growth, and embryo implantation[1][2]. There is currently no evidence that UBTFL1 is a direct therapeutic target, is associated with small-molecule drugs, or acts as a disease biomarker[1][2][5][6].
- Other names
- C11orf27Chromosome 11 open reading frame 27Upstream binding transcription factor, RNA polymerase I-like 1HMGPIPutative upstream-binding factor 1-like protein 1Upstream binding transcription factor like 1
02
Biological functions
Regulation of gene expressionPositive regulation of transcription by RNA polymerase IGeneral transcription initiation by RNA polymerase IProliferation of the inner cell mass and trophectodermal cells in peri-implantation development[1][2][6][7]
03
Disease associations
Other (No direct linkage to diseases such as cancer, inflammation, etc. based on current data)[1][2]
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