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Upstream binding transcription factor, RNA polymerase I-like 7 (pseudogene) (UBTFL7)
- Target
- UBTFL7
- Molecular classification
- Pseudogene
01
Overview
UBTFL7 (Upstream binding transcription factor, RNA polymerase I-like 7) is a human pseudogene, meaning it is a DNA sequence closely related to a protein-coding gene, but lacking functional protein expression due to disabling mutations or regulatory limitations[6][7][9]. It is related to the upstream binding transcription factor family, whose canonical member UBTF plays a crucial role in ribosomal RNA transcription and chromatin remodeling[3][5]. Pseudogenes like UBTFL7 may have non-coding functions, such as acting as competitive endogenous RNAs (ceRNAs) or miRNA decoys, but specific biological or disease roles for UBTFL7 have not been established[8]. UBTFL7 is not recognized as a therapeutic target or biomarker and is typically cataloged for genome annotation purposes only[4][6][7][9].
- Other names
- hCG1990491UBTF like 7upstream binding transcription factor, RNA polymerase I pseudogeneupstream binding transcription factor, RNA polymerase I-like 7 (pseudogene)
02
Mechanism of action
Not applicable
03
Biological functions
Does not encode a protein; may participate in non-coding regulatory functions typical of pseudogenes
04
Disease associations
None established for UBTFL7; some pseudogenes can be involved in regulatory processes affecting cancer or other diseases, but no evidence is available for UBTFL7 specifically[2][8]
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