Target intelligence / Profile preview

Urea

Molecular classification: Small Molecule, Metabolite

Overview

Urea is the primary nitrogenous waste product from protein metabolism in mammals, synthesized in the liver via the urea cycle for ammonia detoxification. It is also widely used as a nitrogen-rich fertilizer and in industrial applications, including the production of plastics and pharmaceuticals. Its ability to disrupt hydrogen bonds makes it useful in protein denaturation studies. Elevated levels in the blood (uremia) are indicative of kidney dysfunction.

Other names: CarbamideIsoureaCarbonyldiamide

Biological functions

Nitrogen excretionProtein denaturation

Disease associations

UremiaKidney diseaseHyperammonemia

Safety considerations

High concentrations can be toxicFertilizer runoff contributing to environmental pollution

Biomarkers

Blood urea nitrogen (BUN) levels for kidney function

Beyond the preview

Go deeper on Urea.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Urea.

Explore the full profile