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v-ral simian leukemia viral oncogene homolog A pseudogene

Molecular classification
Pseudogene, Long non-coding RNA
01

Overview

v-ral simian leukemia viral oncogene homolog A pseudogene" (ENSG00000231525) is classified as a **pseudogene**, meaning it is a genomic DNA sequence that resembles a functional gene (specifically the RALA oncogene) but lacks the ability to produce a functional protein. Pseudogenes typically arise from duplication or retrotransposition events and carry mutations (such as frameshifts or stop codons) that prevent their translation or expression as active proteins[1][2][3]. While most pseudogenes are considered transcriptionally inactive and functionless, some may be transcribed at low levels and can occasionally have regulatory roles at the RNA level, including acting as microRNA sponges or generating regulatory noncoding RNAs[5][6]. However, there is no evidence that this particular pseudogene has any functional or therapeutic relevance, nor is it considered a drug target[4]. Pseudogenes can complicate genetic studies and annotation but are not relevant to pharmacological intervention or biomarker discovery[3][4].

Other names
RALA pseudogeneRalA pseudogene
02

Biological functions

Most pseudogenes do not encode functional proteins, but can sometimes act as regulatory RNA (e.g. microRNA decoys or antisense RNAs in rare cases)
03

Disease associations

CancerOther (potential regulatory impact if transcribed)

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