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V-set and transmembrane domain-containing protein 2B (VSTM2B)
- Target
- VSTM2B
- Molecular classification
- Other (single-pass transmembrane protein; not classified as receptor, enzyme, transporter, ion channel, or transcription factor)
01
Overview
V-set and transmembrane domain-containing protein 2B (VSTM2B) is a predicted single-pass membrane protein encoded by the VSTM2B gene in humans. It is expressed in the brain and spinal cord mantle layer, but its exact molecular function, physiologic role, and mechanism of action remain poorly characterized. There is currently no evidence that VSTM2B functions as a receptor, enzyme, or classical therapeutic target. Some genomic and multi-omic studies list VSTM2B as part of gene panels in diverse biological contexts, but there are no established therapeutic drugs or disease biomarker applications as of the latest data.
- Other names
- VSTM2BV-set and transmembrane domain containing 2BV-set and transmembrane domain-containing protein 2B
02
Biological functions
Unknown (predicted membrane protein; specific biological functions not clearly established)
03
Disease associations
Other (rare associations, e.g., congenital bilateral aplasia of vas deferens; not established in major disease roles such as cancer, inflammation, neurodegeneration, cardiovascular disease, or infection)
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