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Target intelligence / Profile preview
Vacuolar protein sorting 26 homolog B pseudogene 1 (VPS26BP1)
- Target
- VPS26BP1
- Molecular classification
- Other (Pseudogene)
01
Overview
VPS26BP1 (VPS26B pseudogene 1) is a genomic pseudogene related to VPS26B, a retromer complex component involved in intracellular protein transport and endosome-to-Golgi retrograde trafficking. Unlike the functional protein VPS26B, VPS26BP1's sequence is considered a non-coding relic or possibly a regulatory paralog, and there is no evidence it produces a protein or participates directly in cellular transport pathways. Its presence in the human genome may reflect evolutionary history or potential regulatory functions, but it is not a druggable or disease-associated target. If you require information about a retromer complex drug target, refer instead to the protein-coding VPS26B gene, not VPS26BP1.
- Other names
- VPS26B pseudogene 1vacuolar protein sorting 26 homolog B pseudogene 1
02
Biological functions
None established for VPS26BP1, as pseudogenes generally do not encode functional proteins
03
Disease associations
None established; pseudogenes rarely have direct disease associations unless acting in gene regulation. No recognized involvement in cancer, neurodegenerative, or other diseases
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