Vacuolar protein sorting 33B pseudogene

Vacuolar protein sorting 33B pseudogene is a non-protein-coding genomic element related by sequence to the protein-coding gene VPS33B. Pseudogenes arise from gene duplication or retrotransposition events and typically harbor disabling mutations that prevent protein production[5][2][3]. While the coding VPS33B gene is involved in vesicle-mediated protein sorting and associated with multisystem syndromes[1][4][7], the pseudogene itself does not encode a functional protein and is not recognized as a drug target. Pseudogenes may play limited roles in regulating parental gene expression at the RNA or epigenetic level, but there is no evidence for the vacuolar protein sorting 33B pseudogene participating in such mechanisms in a clinically relevant way[5][3][6][9].

Other names

VPS33B pseudogeneVPS33B-related pseudogenePseudogene of vacuolar protein sorting 33B

None (since it is not a therapeutic target, there are no mechanisms of action for drug interaction).