Vagal Afferent Nerve (Gastro-Pulmonary Reflex)

The vagal afferent nerve refers to the sensory fibers of the vagus nerve (cranial nerve X) that transmit information from visceral organs—including the gastrointestinal (GI) tract and lungs—to the central nervous system. These nerves are a critical component of reflex circuits, such as those coordinating gastro-pulmonary responses, and play a key role in homeostatic regulation by relaying mechanical, chemical, and nociceptive signals. They are not a single target, but rather a system of sensory neurons. Therapeutic interventions often target specific receptors or the vagus nerve itself to modulate its activity.

Other names

Vagus Nerve Sensory FibersGastrointestinal Vagal AfferentsPulmonary Vagal AfferentsVagal Sensory Neurons

Modulation of vagal afferent signaling via receptor activation/inhibition; electrical stimulation of vagus nerve.