Various lymphocyte surface antigens

Lymphocyte surface antigens are diverse membrane-bound proteins used to identify and classify various lymphocyte types, including T cells, B cells, and NK cells[1][3][4][5]. The most prominent classification system is the Cluster of Differentiation (CD) nomenclature, designating over 370 distinct molecules with roles in immune cell recognition, activation, antigen presentation, and signaling[4][7]. These antigens serve as important diagnostic markers, therapeutic targets (notably in cancer and immune disorders), and functional regulators of immune responses. Well-known examples include CD3 (pan-T cell marker), CD19 and CD20 (B cell markers), and CD56 (NK cell marker). Their expression profiles guide both basic and clinical immunological applications, including patient selection for biologic therapies, disease monitoring, and immunophenotyping[1][3][4]. Note: To obtain structured information on a specific antigen (e.g., CD20, CD19), query using the precise molecule name. "Various lymphocyte surface antigens" is too generic for direct mapping to a singular canonical target.

Other names

lymphocyte surface markerscluster of differentiation antigensCD antigensleucocyte differentiation antigens

Antibody-dependent cellular cytotoxicity; Complement-mediated cell lysis; Inhibition of cell proliferation; Immune cell depletion