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Vascular Endothelial Growth Factor A Gene Transcription (VEGFA Transcription)
- Target
- VEGFA Transcription
- Molecular classification
- Gene Expression, Transcription
01
Overview
Vascular endothelial growth factor (VEGF) gene transcription refers to the cellular processes that regulate the expression of VEGF-A, a key protein involved in angiogenesis (formation of new blood vessels), vasculogenesis, and vascular permeability. The transcription of the VEGFA gene is tightly regulated by various cis-regulatory elements and trans-acting factors such as HIF-1, Sp1, and Estrogen Receptors.
- Other names
- VEGF-A gene transcriptionVEGFA gene expressionVEGF transcription
02
Biological functions
Regulation of angiogenesisRegulation of vasculogenesisRegulation of vascular permeabilityCell proliferationCell migration
03
Disease associations
CancerDiabetic microvascular complicationsPOEMS syndrome
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