Target intelligence / Profile preview

Vasopressor therapy

01

Overview

Vasopressor therapy is a clinical intervention involving the administration of vasopressor drugs to elevate blood pressure in patients with shock or severe hypotension. This therapy encompasses multiple drug classes that act on different receptors (e.g., adrenergic and non-adrenergic receptors) to constrict blood vessels and/or increase cardiac contractility, but does not refer to a specific molecule or receptor. Common vasopressors include norepinephrine, epinephrine, phenylephrine, vasopressin, and angiotensin II, which target specific receptors to achieve their hemodynamic effects in critical care settings. It is a treatment strategy, not a molecular target.

Other names
vasopressor treatmentvasoactive therapyvasopressor drug therapyvasopressor infusion
02

Mechanism of action

Vasopressor therapy involves the administration of drugs that act on various receptors (e.g., adrenergic and non-adrenergic receptors) to constrict blood vessels and/or increase cardiac contractility, thereby elevating blood pressure.

03

Safety considerations

Risk of ischemia (due to excessive vasoconstriction)ArrhythmiasTissue injury from extravasation

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