VDAC2 pseudogene 5 (VDAC2P5)

VDAC2 pseudogene 5 (VDAC2P5) is a genomic sequence that closely resembles the functional VDAC2 gene but has lost protein-coding capability due to sequence alterations such as mutations and deletions[4][5]. Pseudogenes like VDAC2P5 result from gene duplication or retrotransposition events and are typically classified as processed or unprocessed depending on their structure. VDAC2P5 does not code for a functional voltage-dependent anion channel, and there is no evidence it produces a functional RNA or protein product[4][5]. Although VDAC2 protein-coding gene is highly relevant in mitochondrial metabolism, apoptosis regulation, and is implicated in various diseases[1][3][4], VDAC2P5 itself is not known to have biological activity or therapeutic relevance[4][5]. The VDAC2 family contains multiple pseudogenes (e.g., on chromosomes 1, 2, 12, and 21), but these are not considered functional targets for drug discovery or molecular therapeutics[4][5]. There is nothing misspelled about "VDAC2 pseudogene 5", but it is not a valid target under standard biomedical conventions; it is correctly identified as a pseudogene, not a protein-coding gene or receptor[4][5]. For detailed target information and druggability, you should focus on the functional gene: Voltage dependent anion channel protein 2 (VDAC2)[1][3][4]. VDAC2P5 is a pseudogene and not a therapeutic target, with no known biological or clinical roles, drug interactions, or relevance in biomarker or safety assessments[4][5]. All key functional roles and disease associations pertain to the protein-coding VDAC2 gene.

Other names

VDAC2P5VDAC2 pseudogene 5