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Target intelligence / Profile preview
Very Low-Density Lipoprotein Secretion (VLDL Secretion)
- Target
- VLDL Secretion
- Molecular classification
- Metabolic Process, Lipid Metabolism, Secretion
01
Overview
VLDL secretion is the process by which the liver assembles and releases VLDL particles into the bloodstream for the transport of endogenous triglycerides to peripheral tissues. It is a crucial aspect of lipid metabolism and homeostasis, and its dysregulation is associated with various metabolic disorders including hypertriglyceridemia, atherosclerosis, and non-alcoholic fatty liver disease.
- Other names
- Hepatic VLDL SecretionVLDL ExportTriglyceride Secretion
02
Biological functions
Triglyceride transportLipid homeostasisEnergy distributionCholesterol transport
03
Disease associations
HypertriglyceridemiaAtherosclerosisCardiovascular diseaseNon-alcoholic fatty liver disease (NAFLD)Insulin resistanceMetabolic syndrome
04
Safety considerations
Dysregulation leading to hepatic steatosisContribution to hyperlipidemia and cardiovascular risk
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