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Vesicular integral-membrane protein VIP36 (LMAN2)

Target: LMAN2
Molecular classification: Other (specifically, type I transmembrane lectin)

Overview

Vesicular integral-membrane protein VIP36 (LMAN2) is a type I transmembrane lectin that functions as an intracellular lectin in the early secretory pathway. It binds to high-mannose type glycoproteins and shuttles between the endoplasmic reticulum and Golgi apparatus, thereby playing a role in protein sorting and trafficking. There is no current evidence that it serves as a therapeutic target or biomarker.

Other names: C5orf8GP36BVIP36Glycoprotein GP36bLectin mannose-binding 2Vesicular integral-membrane protein 36epididymis secretory sperm binding proteinvesicular integral protein of 36 kDa

Biological functions

Intracellular lectin in early secretory pathwaybinding high-mannose glycoproteinsshuttling between the endoplasmic reticulum and Golgi apparatus

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