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Vessel Dilation
- Molecular classification
- Physiological Process, Homeostatic Mechanism
01
Overview
Vessel dilation, or vasodilation, is a physiological process involving the widening of blood vessels due to the relaxation of smooth muscle cells within their walls. This leads to decreased vascular resistance, increased blood flow, and lower blood pressure. It is regulated by various endogenous mediators and is clinically relevant for treating conditions like hypertension and heart failure. Excessive vasodilation can lead to hypotension and is also observed in pathological conditions like anaphylaxis.
- Other names
- VasodilationBlood vessel dilation
02
Mechanism of action
Relaxation of vascular smooth muscle, leading to increased vessel diameter and blood flow.
03
Biological functions
Regulation of blood pressureRegulation of blood flowOxygen deliveryNutrient deliveryThermoregulation
04
Disease associations
HypertensionHypotensionHeart failurePulmonary hypertensionPreeclampsia/eclampsiaShockAnaphylaxisInflammation
05
Safety considerations
HypotensionDizzinessFaintingReflex tachycardiaDrug interactions
06
Interacting drugs
Nitroglycerin
5 more in the full profile.
07
Biomarkers
Blood pressureVascular resistanceNitric oxide levelsEndothelin levels
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