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Target intelligence / Profile preview
Vibrio cholerae O1 (V. cholerae O1)
- Target
- V. cholerae O1
- Molecular classification
- Bacterium, Gram-negative bacterium, Pathogen
01
Overview
Vibrio cholerae O1 is a Gram-negative bacterium responsible for causing epidemic and pandemic cholera. It is characterized by its O1 serogroup antigen and its ability to produce cholera toxin (CT) and toxin-coregulated pilus (TCP), both of which are essential for its virulence. Infection occurs through ingestion of contaminated water or food, leading to severe watery diarrhea and dehydration.
- Other names
- Cholera O1Vibrio cholerae serogroup O1
02
Mechanism of action
Antibiotics inhibit bacterial growth or kill bacteria; rehydration solutions replenish lost fluids and electrolytes.
03
Biological functions
PathogenesisColonizationToxin productionInfection
04
Disease associations
CholeraDiarrheal diseaseGastrointestinal infection
05
Safety considerations
Antibiotic resistanceSpread of infectionDehydration and electrolyte imbalance
06
Interacting drugs
Antibiotics (e.g., tetracycline, doxycycline, azithromycin)
1 more in the full profile.
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