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Target intelligence / Profile preview
Vibrio cholerae O1 El Tor Inaba (V. cholerae O1 El Tor Inaba)
- Target
- V. cholerae O1 El Tor Inaba
- Molecular classification
- Bacterium, Pathogen
01
Overview
Vibrio cholerae O1 El Tor Inaba is a specific serotype and biotype of the bacterium *Vibrio cholerae*, the causative agent of epidemic cholera. It is characterized by the production of cholera toxin and toxin-coregulated pilus, key virulence factors. Prevention strategies include oral killed whole-cell vaccines and water sanitation.
- Other names
- Cholera O1 El Tor InabaVibrio cholerae O1 InabaEl Tor Inaba
02
Mechanism of action
Oral cholera vaccines induce antibacterial intestinal antibodies preventing bacterial attachment/colonization and anti-toxin antibodies blocking cholera toxin binding to mucosal surfaces.
03
Biological functions
ColonizationToxin productionInfectionBiofilm formation
04
Disease associations
CholeraInfection
05
Safety considerations
Potential for serotype-specific immunity after infection or vaccination, requiring broad coverage in vaccines.
06
Interacting drugs
Dukoral (oral cholera vaccine)
1 more in the full profile.
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