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Vibrio cholerae O139
- Molecular classification
- Bacterium, Gram-negative bacterium
01
Overview
Vibrio cholerae O139 is a serogroup of the bacterium Vibrio cholerae responsible for epidemic cholera. It is a gram-negative bacterium characterized by its unique O-antigen polysaccharide and polysaccharide capsule. It possesses key virulence factors such as cholera toxin (CTX), a type II secretion system, and biofilm formation genes, enabling it to cause severe diarrheal disease.
- Other names
- V. cholerae O139Vibrio cholerae O139 BengalO139 Bengal
02
Mechanism of action
Antibiotics target essential bacterial processes, leading to cell death or growth inhibition. Rehydration therapy replenishes lost fluids and electrolytes.
03
Biological functions
PathogenesisColonizationToxin productionBiofilm formationInfection
04
Disease associations
CholeraDiarrheal diseaseInfection
05
Safety considerations
Antibiotic resistanceSpread of infectionDehydration complications (e.g., kidney failure, shock)
06
Interacting drugs
Rehydration solutions (e.g., oral rehydration salts)
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