Vimentin-type intermediate filament-associated coiled-coil protein (VMAC)

Vimentin-type intermediate filament-associated coiled-coil protein (VMAC) is a predicted cytoplasmic protein potentially associated with the intermediate filament system, encoded by the gene VMAC (HGNC: 33803, NCBI Gene: 400673, UniProt Q2NL98)[2][3]. It is classified as a member of the intermediate filament family, though there is no strong evidence establishing its therapeutic relevance, specific biological activity, or association with disease. The protein is predicted to localize to the cytoplasm and interact with type III intermediate filaments such as vimentin, but detailed characterization of its function, mechanism, biomarker status, and safety profile is lacking[2][3]. No known drugs target this protein, and it is not established as a therapeutic or diagnostic target in the current literature. Note on correctness: The entity is a low-confidence, predicted or computationally-annotated protein, possibly with species-specific entries in databases (e.g., in Danio rerio and Mus musculus)[4][5], and does not appear in major reviews or primary literature as a target of clinical significance. Its utility as a target is therefore not established and its inclusion as a canonical target is not supported by direct functional or disease evidence in human medicine.

Other names

VMACVimentin type intermediate filament associated coiled-coil proteinVimentin-type IF-associated coiled-coil protein

Not established