Viral Entry Inhibition

Viral entry inhibition is a therapeutic strategy and drug class aimed at disrupting the initial stages of viral infection by blocking the virus from entering the host cell. This is achieved by interfering with attachment, co-receptor binding, or fusion processes involving key viral and host cell molecules. Entry inhibitors are primarily used as antiretroviral agents, notably in HIV treatment, and are being explored for other viral infections.

Other names

Entry inhibitorsViral entry blockersViral attachment inhibitorsViral fusion inhibitors

Inhibition of viral attachment, co-receptor binding, or fusion with the host cell membrane, preventing viral entry and subsequent replication.