Viral-induced radicals

The term "viral-induced radicals" refers to a biological phenomenon, specifically the production of free radicals (including reactive oxygen species [ROS] and reactive nitrogen species [RNS]) that are generated in host cells in response to viral infection. These are byproducts of cellular processes triggered during viral pathogenesis, involving pathways like NADPH oxidase (NOX/DUOX) family enzymes and nitric oxide (•NO) synthase, leading to oxidative stress. It is not a single, discrete molecular target, receptor, enzyme, transporter, or other identifiable drug target. Therefore, it cannot be characterized using a structured framework for therapeutic targets. Research into therapeutic approaches related to this phenomenon focuses on targeting upstream regulators or downstream effects, such as ferroptosis modulators, iron metabolism pathways, or ROS-generating enzymes, rather than the 'radicals' themselves.

Other names

free radicals induced by viral infectionreactive oxygen species (ROS) induced by viral infectionreactive nitrogen species (RNS) induced by viral infection