Virus-infected cells presenting adenovirus antigens

Virus-infected cells presenting adenovirus antigens are host cells that have been infected by adenoviruses and subsequently display viral antigens on their surface, primarily via the major histocompatibility complex (MHC) class I pathway. These presented antigens are recognized by the immune system, particularly cytotoxic T lymphocytes (CTLs), which target and eliminate infected cells to control infection. Adenoviruses have evolved immune evasion mechanisms, such as the E19 protein, which inhibits MHC class I presentation. These cells serve as key targets for vaccine development and cancer therapy using oncolytic or gene therapy vectors.

Other names

Adenovirus-infected cells presenting viral antigensAdenovirus-infected cells displaying MHC-I-peptide complexes

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