Virus-infected or malignant host cell

"Virus-infected or malignant host cell" is not a specific molecular target but rather a broad description of cells that have either been infected by viruses or have undergone malignant transformation (become cancerous). These cells are characterized by the presence of foreign genetic material—either viral genomes in the case of infection[3][4], or oncogenic mutations in the case of malignancy. Both types can evade normal immune surveillance and may display altered surface markers, metabolic changes, and abnormal growth properties. While many therapies aim to selectively target these abnormal cells (for example, antiviral drugs targeting infected cells or chemotherapies targeting cancer cells), "virus-infected or malignant host cell" itself does not refer to a single molecule, receptor, enzyme, transporter, or other canonical drug target class. Instead, it is an umbrella term encompassing diverse cellular states resulting from infection[3][4] or oncogenic processes. Because this entry refers to a heterogeneous population rather than a defined molecular entity with specific structure and function—and lacks standard nomenclature—it should be considered incorrect as a canonical therapeutic target according to standard conventions.

Other names

Infected cellMalignant cellVirus-infected cellCancerous cell