Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Visceral Afferent Nerves (GVA)
- Target
- GVA
- Molecular classification
- Sensory Neuron, Afferent Nerve, Nerve Fiber
01
Overview
Visceral afferent nerves (GVAs) are sensory nerve fibers that transmit information from internal organs, glands, and blood vessels to the CNS. They are crucial for monitoring the body's internal environment and regulating homeostasis by relaying sensory input such as pain, reflex sensations, chemical changes, and mechanical events. They are potential therapeutic targets for visceral pain conditions.
- Other names
- General Visceral Afferent FibersVisceral Sensory Neurons
02
Mechanism of action
Modulation of sensory input from internal organs to the CNS
03
Biological functions
Sensory transductionHomeostasis regulationReflex signalingPain signalingInteroceptionGut-brain signaling
04
Disease associations
Chronic abdominal painVisceral hypersensitivityIrritable bowel syndrome (IBS)Inflammatory bowel disease (IBD)Referred pain
05
Safety considerations
Potential for off-target effects on other sensory pathwaysDevelopment of tolerance to therapeutic interventionsComplexity of visceral pain mechanisms
06
Interacting drugs
Bradykinin receptor antagonists
1 more in the full profile.
Beyond the preview
Go deeper on Visceral Afferent Nerves (GVA).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Visceral Afferent Nerves (GVA).