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Internal tamponade agents are substances used in vitreoretinal surgery to provide mechanical support and prevent fluid from accumulating under the retina, facilitating its reattachment. These agents include gases (air, SF₆, C₂F₆, C₃F₈), silicone oils, and heavy silicone oils/perfluorocarbon liquids. They function based on physical properties like surface tension and buoyancy, rather than through biological interactions. Their use is indicated in retinal detachment, macular hole repair, and proliferative vitreoretinopathy. Potential complications include cataract formation, glaucoma, and re-detachment.
Mechanical barrier against subretinal fluid ingress, supporting retinal reattachment through surface tension and buoyancy.
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