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Target intelligence / Profile preview
Vitrin (VIT)
- Target
- VIT
- Molecular classification
- Other: Extracellular matrix (ECM) protein; not classified as enzyme, receptor, ion channel, transporter, or transcription factor
01
Overview
Vitrin (VIT) is a secreted extracellular matrix protein that may promote matrix assembly and cell adhesiveness. It plays a role in neural development, notably in spinal cord formation by regulating the proliferation and differentiation of neural stem cells. High levels of expression in parts of the brain suggest a likely developmental or maintenance role in the central nervous system. There is no current evidence supporting its use as a drug target, biomarker, or its involvement as a receptor, enzyme, or other canonical druggable protein class. Diseases associated with this gene include certain meningiomas, though functional details for pathogenesis are limited.
- Other names
- VitrinVITVITRNUNQ647/PRO1277VIT1vitrin (lowercase)
02
Biological functions
Matrix assemblyCell adhesivenessRegulation of proliferation and differentiation of neural stem cellsRole in spinal cord formation
03
Disease associations
Angiomatous meningiomaTransitional meningioma (based on disease associations, though causal or mechanistic involvement is unclear)Other: Potential role in neural development disorders (inferred from high brain expression and function)
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