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Voltage dependent anion channel 1 pseudogene 2 (VDAC1P2)

Target: VDAC1P2
Molecular classification: Other (specifically, pseudogene)

Overview

Voltage dependent anion channel 1 pseudogene 2 (VDAC1P2) is a non-functional genomic sequence similar to the protein-coding gene for voltage-dependent anion channel 1 (VDAC1). While the canonical VDAC1 protein forms an important mitochondrial outer membrane channel implicated in cellular energy metabolism, apoptosis, and disease, the pseudogene VDAC1P2 does not produce a functional protein and is therefore not considered a therapeutic or biological target. VDAC1P2 may exist due to gene duplication or retrotransposition events during evolution, but current evidence does not support an active biological role or relevance to therapy.

Other names: VDAC1P2voltage-dependent anion-selective channel 1 pseudogene 2

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