Target intelligence / Profile preview

Voltage dependent anion channel 1 pseudogene 3 (VDAC1P3)

Target
VDAC1P3
Molecular classification
Other (pseudogene)
01

Overview

VDAC1P3 is one of multiple processed pseudogenes related to the voltage-dependent anion channel 1 (VDAC1) gene in the human genome. It does not encode a functional protein product. Pseudogenes like VDAC1P3 may have minor regulatory effects through non-coding RNA in rare contexts, but VDAC1P3 is expressed at very low levels in a few tissues and has not been implicated in any disease or biological process. The parental gene, VDAC1, encodes a mitochondrial outer membrane channel involved in metabolic regulation and disease, but those functions do not apply to VDAC1P3[2][6][7].\n\nKey points:\n- VDAC1P3 is not a functional protein or drug target.\n- No known biological or disease relevance or biomarker role exists for VDAC1P3 at present.\n- Do not confuse VDAC1P3 with VDAC1, which is a mitochondrial ion channel and a target in multiple diseases.

Other names
VDAC1 pseudogene 3VDAC1P3
02

Biological functions

None established for VDAC1P3 itself; not a protein-coding geneHowever, some VDAC pseudogenes may have a regulatory RNA function in specific contexts through ceRNA (competing endogenous RNA) effects, but no evidence is reported for VDAC1P3 specifically
03

Disease associations

None established for VDAC1P3.Some VDAC1 pseudogenes, notably VDAC1P8, have been associated with altered expression in acute myeloid leukemia (AML), but VDAC1P3 shows only very low-level expression and no known disease correlation

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