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Voltage dependent anion channel 1 pseudogene 5 (VDAC1P5)

Target: VDAC1P5
Molecular classification: Other — Processed pseudogene; not an ion channel, enzyme, receptor, or other standard classification

Overview

Voltage dependent anion channel 1 pseudogene 5 (VDAC1P5) is a processed pseudogene located in the human genome that is related by sequence to the functional VDAC1 gene. VDAC1 encodes a mitochondrial outer membrane protein involved in anion and metabolite exchange, apoptosis, and cellular metabolism[1][4]. In contrast, VDAC1P5 has no coding capacity and is not translated into a functional protein. Some VDAC1 pseudogenes can be transcribed and may play roles in gene regulation or act as competing endogenous RNAs in specific tissues or disease models, but VDAC1P5 is not documented to have such activity[2]. Therefore, VDAC1P5 is not a direct target for drugs and has no documented role in human disease or physiology.

Other names: VDAC1P5

Biological functions

Other — Pseudogenes generally lack classical biological function; some may have regulatory roles via non-coding RNA, but VDAC1P5-specific functions are not reported

Disease associations

Other — There is no evidence linking VDAC1P5 to disease directly; some VDAC1 pseudogenes (such as VDAC1P8) may have regulatory roles in certain cancers, but this has not been shown for VDAC1P5

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