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**Voltage dependent anion channel 1 pseudogene 9 (VDAC1P9)** is a *pseudogene* based on available naming and classification. It is not an active gene encoding a functional protein, but a non-functional segment of DNA with sequence similarity to the gene encoding voltage dependent anion channel 1 (VDAC1)[1][5]. Pseudogenes like VDAC1P9 are generally not considered therapeutic targets—they do not produce proteins that could directly serve as drug targets or biomarkers. There is no evidence in curated genetic or pharmaceutical databases that VDAC1P9 is involved in biological function, disease pathology, drug interaction, or used as a biomarker. **Clarification:** - VDAC1P9 should not be confused with **Voltage dependent anion channel 1 (VDAC1)**, which is a protein-coding gene with well-documented roles in mitochondrial function, metabolism, apoptosis, and as a possible therapeutic target in several diseases[3][7]. - However, *VDAC1P9* as a pseudogene is with high certainty **not a therapeutic target** and has no established biological or clinical significance. **Summary of issues:** - VDAC1P9 is a pseudogene, not an active gene or protein. - No evidence for biological function, drug interaction, or disease involvement.
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