Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Voltage-gated potassium channel subunit Kv1.1 (Kv1.1)
- Target
- Kv1.1
- Molecular classification
- Ion channel, Voltage-gated potassium channel
01
Overview
Kv1.1 is a voltage-gated potassium channel subunit essential for regulating neuronal excitability and repolarizing cell membranes after action potentials. It plays a critical role in nerve signaling and communication within the central nervous system. Mutations or dysfunctions are associated with neurological disorders such as Episodic Ataxia Type 1 and Isaacs syndrome.
- Other names
- KCNA1HuK1RBK1MBKVoltage-gated potassium channel HBK1Voltage-gated K+ channel HuKIAEMK
02
Mechanism of action
Modulation of potassium ion flow across cell membranes
03
Biological functions
Regulation of membrane potentialRepolarization following action potentialsPrevention of neuronal hyperexcitabilityTransmembrane transport of potassium ions
04
Disease associations
Episodic Ataxia Type 1 (EA type I)Isaacs syndromeEpilepsyCardiac arrhythmias
05
Safety considerations
Potential for altered neurocardiac excitabilityAutoimmune targeting of Kv channels
Beyond the preview
Go deeper on Voltage-gated potassium channel subunit Kv1.1 (Kv1.1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Voltage-gated potassium channel subunit Kv1.1 (Kv1.1).