Vomeronasal 1 receptor 1 pseudogene (VN1R1P)

The Vomeronasal 1 receptor 1 pseudogene (VN1R1P) refers to a nonfunctional DNA segment that resembles the protein-coding gene for vomeronasal 1 receptor 1, a receptor involved in pheromone detection in animals. As a pseudogene, VN1R1P contains mutations or deletions that prevent it from encoding a functional receptor protein, and it does not participate in known biological pathways or disease processes. Pseudogenes such as this arise from gene duplication or retrotransposition followed by disabling mutations and are considered genomic relics with no current biological activity, though some can occasionally have regulatory roles in rare cases[1][2][5][6]. In the human genome, most vomeronasal receptor genes, including those of the VN1R1 family, are pseudogenized and therefore do not contribute to pheromone sensing[5][6]. Key points: - VN1R1 pseudogene is not a therapeutic target—it does not encode a functional protein, receptor, enzyme, or transporter, and has no known biological or pathological function in humans[1][2][6]. - Its status as a pseudogene means there are no drugs, biomarkers, or safety concerns associated with it. - The inclusion of this entry as a molecular drug target is incorrect[1][2].

Other names

VN1R1 pseudogeneVN1R1Pvomeronasal receptor 1a pseudogene