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Vomeronasal 1 receptor 13 pseudogene (VN1R13P)

Target: VN1R13P
Molecular classification: Pseudogene (human), Vomeronasal receptor family 1 (V1R family), Historically/structurally: G protein-coupled receptor (GPCR) (functional members of this family are class A GPCRs, but as a pseudogene, it is non-functional in humans)

Overview

VN1R13P (Vomeronasal 1 receptor 13 pseudogene) is a human pseudogene belonging to the vomeronasal 1 receptor (V1R) gene family, which, in other mammals, encodes G protein-coupled receptors responsible for pheromone detection via the vomeronasal organ. However, in humans, VN1R13P is non-functional and does not produce a protein. This is typical for most members of the V1R family in humans, which have lost their function during primate evolution[6][7][1][3][9]. VN1R13P is thought to be the relic of an evolutionary contraction in the vomeronasal receptor gene family, reflecting the vestigial nature of the vomeronasal system in humans[7].

Other names: VNR6I4PbA373D17.3hs6V1-4pVomeronasal 1 receptor 1 pseudogeneVN1R13P

Mechanism of action

Not applicable (no functional protein product in humans)

Biological functions

None in humans (pseudogene, no known function)Functional V1Rs in other species are involved in pheromone detection/sensory perception

Disease associations

None reported (no evidence for involvement in disease due to pseudogene status in humans)

Safety considerations

None known (not therapeutically targeted or expressed)

Interacting drugs

None known (not functionally expressed in humans, so no drug interaction is documented)

Biomarkers

None known (not expressed, not used as a biomarker)

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