Vomeronasal type-1 receptor 60 pseudogene (VN1R60P)

Vomeronasal type-1 receptor 60 pseudogene (VN1R60P, ENSG00000261048) is classified as a pseudogene in the human genome, meaning it does not produce a functional protein product. VN1R pseudogenes are derived from the vomeronasal receptor family, a group of G protein-coupled receptors (GPCRs) implicated in pheromone detection in many vertebrates. However, in humans, most of these genes—including VN1R60P—have lost function due to accumulated mutations. The submitted name "vomeronasal type-1 receptor 4 pseudogene" appears to be a misidentification; ENSG00000261048 and VN1R60P correctly refer to "vomeronasal type-1 receptor 60 pseudogene". As a pseudogene, VN1R60P is neither a functional receptor nor a recognized therapeutic target. No evidence supports its use as a biomarker, its involvement in disease, or any safety/therapeutic concerns. The family of intact vomeronasal type-1 receptors are part of the olfactory GPCR superfamily, but humans have mostly lost these receptors as functional proteins. Thus, this entry is not considered a bona fide therapeutic target and lacks known function, disease association, or drug interaction in humans. VN1R60P is a pseudogene, not a drug target or functional receptor, and should not be used as a canonical biological or therapeutic entity in humans. The original query contains some confusion regarding its identity and target relevance.

Other names

ENSG00000261048vomeronasal 1 receptor 60 pseudogene