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Von Willebrand factor A domain containing 5B pseudogene
- Molecular classification
- Other (Pseudogene)
01
Overview
The von Willebrand factor A domain containing 5B pseudogene (ENSG00000258823, LOC100421646) is an unprocessed partial pseudogene located on chromosome 22, homologous to exons 23–34 of the VWF gene[4]. It contains multiple nonsense and splice-site mutations and does not encode a functional protein[2][3]. While the functional von Willebrand factor is a key adhesive glycoprotein in hemostasis, mediating platelet adhesion and acting as a carrier for Factor VIII, the pseudogene does not participate in these processes[4][1]. It should not be confused with the functional gene or protein and is not considered a therapeutic target nor used in clinical assays or as a biomarker[4][2][3]. In summary, von Willebrand factor A domain containing 5B pseudogene is a nonfunctional pseudogene and should not be regarded as a therapeutic target or biologically relevant molecule for drug development or biomarker purposes.
- Other names
- LOC100421646ENSG00000258823VWF pseudogenevon Willebrand factor A domain containing 5B pseudogene
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