Target intelligence / Profile preview

Von Willebrand factor A domain-containing protein 5B1 (VWA5B1)

Target: VWA5B1
Molecular classification: Other (contains a von Willebrand factor A (VWA) domain; not established as a receptor, enzyme, transporter, or transcription factor)

Overview

Von Willebrand factor A domain-containing protein 5B1 (VWA5B1) is a member of the von Willebrand factor A (VWA) domain-containing protein family. It is a protein-coding gene with currently poorly defined biological functions in human physiology or pathology. The protein is predicted to be extracellular, and its gene is associated with certain inherited diseases (including Usher syndrome type If and Niemann–Pick disease type C2), but there is no direct evidence for its causal involvement, nor is it established as a classical therapeutic target, receptor, enzyme, transporter, or transcription factor[5][3]. No drugs are known to modulate VWA5B1, and major databases do not currently list it as a receptor or validated target for therapeutic intervention. Its role may be structural or involved in extracellular protein-protein interactions, but this remains speculative[5][3].

Other names: FLJ32784VW5B1Von Willebrand factor A domain containing 5B1

Biological functions

Unknown/unclear in literatureMay play a structural role due to VWA domain (inferred from domain homology; not established by direct functional studies)

Disease associations

Usher syndrome, type IfNiemann–Pick disease, type C2Other (gene-disease association, but causal or functional link unclear)

Beyond the preview

Go deeper on Von Willebrand factor A domain-containing protein 5B1 (VWA5B1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Von Willebrand factor A domain-containing protein 5B1 (VWA5B1).

Explore the full profile