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WAP four-disulfide core domain 15 family pseudogene

Molecular classification
Other, Pseudogene
01

Overview

WAP four-disulfide core domain 15 family pseudogene (ENSG00000283142) is classified as a **pseudogene** and not a protein-coding gene[3][2]. Pseudogenes are genomic sequences similar to known genes but are generally considered non-functional due to disabling mutations or lack of regulatory elements required for expression. The name suggests a relation to the WAP (Whey acidic protein) four-disulfide core domain protein family, which are small secreted proteins characterized by a domain containing eight conserved cysteines that form four disulfide bonds, providing protease inhibitor, antibacterial, and immunomodulatory functions in other, functional family members[1][4]. However, as a pseudogene, ENSG00000283142 does not encode a functional protein, is not associated with known biological function or disease roles, and is not considered a drug target or biomarker[3][2]. There are no known aliases beyond its identifier, and it is not associated with any drugs, therapeutic mechanisms, or established clinical safety concerns. This gene is sometimes referenced in genomic databases under previous identifiers such as GC20M045139, but always as a nonfunctional pseudogene[3]. No evidence suggests involvement in disease, therapeutic targeting, or utility as a biomarker. If you are seeking information about active members of the WAP four-disulfide core domain family, such as WFDC2 or WFDC12, refer to those entries, as they perform various biologically relevant roles[4][5][6].

Other names
ENSG00000283142GC20M045139

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