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Target intelligence / Profile preview
WASP family homolog 6, pseudogene (WASH6P)
- Target
- WASH6P
- Molecular classification
- Other (Pseudogene), Actin-binding protein (predicted function), Arp2/3 complex-associated protein (predicted)
01
Overview
WASP family homolog 6, pseudogene (WASH6P) is officially classified as a pseudogene in humans, meaning it is a DNA sequence related to a functional gene that does not produce a functional protein[1][2]. While predicted functional annotations suggest possible roles in alpha- and gamma-tubulin binding, Arp2/3 complex-mediated actin nucleation, and endosomal trafficking, these are inferred based on homology and not experimentally confirmed in humans[1][3][4][7]. WASH6P is part of the WASH family, involved in actin dynamics, but unlike the functional paralog WASHC1, WASH6P has no established protein product or direct biological activity. It is not considered a true drug target, does not have disease associations, biomarkers, or known safety concerns due to its pseudogene status[1][2][6]. Alternative names include CXYorf1 and FAM39A, but WASH6P is the canonical abbreviation.
- Other names
- CXYorf1FAM39AWASHWAS protein family homolog 6, pseudogeneactin nucleation promoting factorfamily with sequence similarity 39, member A
02
Mechanism of action
None reported
03
Biological functions
Actin nucleation (predicted)Alpha-tubulin binding (predicted)Gamma-tubulin binding (predicted)Endosomal transport (predicted)Exocytosis (predicted)Actin polymerization regulation (predicted)
04
Disease associations
None established; WASH6P is a pseudogene and not implicated in disease directly
05
Safety considerations
None reported
06
Interacting drugs
None reported; as a pseudogene, WASH6P does not encode a functional target for drug interaction
07
Biomarkers
None reported
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