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WD repeat-containing protein 62 pseudogene

Molecular classification
Pseudogene
01

Overview

WD repeat-containing protein 62 pseudogene is a genomic sequence in humans related by homology to the functional WD repeat-containing protein 62 gene (WDR62), which is involved in cerebral cortical development[3][5]. However, as a pseudogene, this locus (ENSG00000259109) does not produce a functional protein product, is not established as a druggable or biologically active target, and has no recognized pathophysiological or therapeutic significance. Pseudogenes are often annotated due to their homology to coding genes, but lack canonical biological function unless specific regulatory or rare coding potential is experimentally validated. No such function is currently attributed to WD repeat-containing protein 62 pseudogene. Clarification & Correction: This entry does not refer to the functional "WD repeat-containing protein 62" (WDR62), an important protein involved in neurodevelopment[1][5][3]. Instead, it refers to its pseudogene, which—by current understanding in genomics and biomedicine—does not encode an active protein or therapeutic target[2][5]. If the intention was to reference the functional gene or protein, the correct Ensembl ID is ENSG00000075702 ("WD repeat domain 62"), not ENSG00000259109. Summary of key points: - ENSG00000259109 is a *pseudogene*, not a protein-coding gene, and has no established role as a therapeutic target. - Searchable databases and scientific sources do not assign aliases, biological function, disease association, or known regulatory or drug-interaction roles to this pseudogene[2][5]. - There is no reason to select this as a pharmaceutical or biological target for drug discovery or biomarker purposes. - *If you intended to refer to the functional gene/protein, please see WDR62 (Ensembl: ENSG00000075702) instead[5].*

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