Target intelligence / Profile preview

WD repeat-containing protein 64 (WDR64)

Target
WDR64
Molecular classification
Other, WD repeat-containing protein, Beta-propeller protein
01

Overview

WD repeat-containing protein 64 (WDR64) is a member of the WD repeat protein family, characterized by the presence of multiple WD40 repeats that typically fold into a β-propeller structure and serve as platforms for reversible protein-protein interactions, rather than possessing any enzymatic or receptor activity[1][2][8]. WDR64 is a human protein encoded by the WDR64 gene and is highly conserved across eukaryotes[3][7][8]. While proteins in this family are implicated in diverse cellular processes—such as signal transduction, cell cycle control, RNA processing, and cytoskeleton organization—the specific biological function and disease relevance of WDR64 itself remain uncharacterized, and there is no evidence linking it directly to therapeutic targeting or known drug interactions[3][8][1]. The current data indicate that its primary molecular role is as a scaffold for multiprotein complex formation without direct catalytic or receptor function[1][2].

Other names
WD repeat domain 64FLJ32978WDR64
02

Biological functions

Protein-protein interaction scaffoldAssembly of multiprotein complexes
03

Disease associations

Other

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