WD repeat domain 59 pseudogene (WDR59P)

The WD repeat domain 59 pseudogene (ENSG00000261458) is a non-coding, non-functional derivative of a WD repeat domain-containing gene. It does not encode a protein and is categorized as a pseudogene, meaning that it has sequence similarity to the functional WD repeat domain 59 gene but has acquired mutations that prevent it from being expressed as a functional protein. The WD repeat domain protein family is characterized by conserved domains that often serve as scaffolds for protein-protein interactions and are broadly involved in a variety of cellular processes, including signal transduction, gene regulation, and chromatin organization[1]. However, pseudogenes such as this have lost the ability to perform such functions and do not represent therapeutic targets or druggable entities[3].

Other names

WD repeat domain 59 pseudogeneENSG00000261458