Target intelligence / Profile preview

WD repeat domain 86 (WDR86)

Target
WDR86
Molecular classification
WD repeat domain-containing protein, Other (not a receptor, enzyme, transporter, ion channel, or transcription factor)
01

Overview

WD repeat domain 86 (WDR86) is a protein coding gene that belongs to the WD repeat domain-containing protein family, characterized by tandem repeats that typically form a β-propeller structure facilitating protein-protein interactions[1][3][5][6]. It is expressed in many human tissues, with no distinct tissue specificity, and is not currently known to function as a receptor, enzyme, transporter, or transcription factor[4][7]. Diseases such as hypophosphatasia have been noted in association datasets, but no concrete evidence links WDR86 mechanistically to disease causation or progression. There are no known drugs, validated disease biomarkers, or established safety concerns related to WDR86 at present[4]. The canonical name and abbreviation are correct and consistent in major biological databases. If you need further structured information or have therapeutic context, additional molecular functional studies may be required because current data is limited to gene/protein annotation and indirect disease associations.

Other names
WD repeat-containing protein 86WDR86WDR86_HUMAN (UniProt)GC07M150709 (GeneCards identifier)GC07M151072GC07M144889Q86TI4 (UniProtKB/Swiss-Prot)
02

Biological functions

Protein-protein interactionsPossibly involved in nuclear protein regulationOther (precise cellular or molecular function not well defined in research)
03

Disease associations

Hypophosphatasia, infantile formHypophosphatasia (general)Other (limited and indirect associations, often based on data integration rather than mechanistic studies)

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