Target intelligence / Profile preview

West Nile Virus (WNV)

Target
WNV
Molecular classification
Virus, Flavivirus
01

Overview

West Nile virus (WNV) is a mosquito-borne, single-stranded RNA virus belonging to the family Flaviviridae and genus Flavivirus. It primarily infects birds but can also infect humans, horses, and other mammals. WNV infection can range from asymptomatic to severe neuroinvasive disease. Prevention focuses on reducing mosquito exposure as there are no approved vaccines or specific antiviral treatments.

02

Mechanism of action

N/A

03

Biological functions

Viral replicationHost cell entryModulation of host immune response
04

Disease associations

InfectionEncephalitisMeningitisPoliomyelitisWest Nile fever
05

Safety considerations

Neuroinvasive diseaseIncreased risk with age and immunocompromised statusLack of specific antiviral treatment

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