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Target intelligence / Profile preview
West Nile virus envelope protein
- Molecular classification
- Viral structural protein, Glycoprotein
01
Overview
The West Nile virus envelope protein (E protein) is a major structural glycoprotein on the viral surface, essential for host cell attachment and entry via membrane fusion. It is a key target for neutralizing antibodies and antiviral drug/vaccine development.
- Other names
- WNV E proteinEnvelope protein
02
Biological functions
Viral attachmentMembrane fusionEntry into host cell
03
Disease associations
Infection
04
Safety considerations
Potential for off-target effects in antiviral developmentEvasion of neutralizing antibodies through mutations
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