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Wolf-Hirschhorn syndrome candidate 1-like 1 pseudogene

Molecular classification
Other (Pseudogene)
01

Overview

Wolf-Hirschhorn syndrome candidate 1-like 1 pseudogene (ENSG00000255174) is a human genomic sequence classified as a pseudogene, related in sequence to the WHSC1L1 gene. Pseudogenes are DNA sequences resembling known genes but are generally non-functional due to mutations that prevent their transcription or translation into biologically active proteins[5][8]. There is no evidence that this pseudogene encodes a protein or acts as a functional molecular target. Its functional relatives — such as WHSC1 (NSD2) and WHSC1L1 (NSD3) — play roles in gene regulation (histone methylation), cancer, and development, but the pseudogene does not participate in these processes[1][7]. No drugs directly target pseudogenes, nor do they serve as recognized biomarkers or therapeutic targets.

Other names
WHSC1L1PNSD3P
02

Disease associations

Functional genes related to this family, such as WHSC1 and WHSC1L1, are involved in Wolf-Hirschhorn syndrome and some cancers, but not the pseudogene itself

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